Grants

2020-2022 "Structure and function of fumarate-adding gltcyl radical enzymes: biochemistry, modeling and application" BETHOVEEN LIFE 2018/31/F/NZ1/01856; principal investigator: Maciej Szaleniec, investigators: Agnieszka M. Wojtkiewicz, Anna Sekuła (PhD student)

2019-2020 "Development of lipase-based catalysts" Grupa Azoty Zakłady Azotowe "Puławy" S.A .; principal investigator: Maciej Guzik, investigators: Beata Mrugała, Mateusz Tataruch

2019-2022 "Technology for biorefining vegetable oils for the production of advanced composite materials" Strategic program of scientific research and development works "Modern material technologies" - TECHMATSTRATEG2 / 407507/1 / NCBR / 2019; project manager: Maciej Guzik, investigators: Tomasz Witko, Olga Zastawny, Adam Kaczmarski, Adam Szeligowski

2018-2020 "Tungsten-Containing Aldehyde Oxidoreductase from Aromatoleum aromaticum - Study of Catalytic Reaction Mechanism" PRELUDIUM 2017/27/N/ST4/02676 - project leader: mgr inż. A.Winiarska, scientific supervisor: prof.
M.Szaleniec)

2017-2020 "The mechanism of regioselective oxidative dehydrogenation of 3-ketosteroids catalyzed by Δ1-cholest-4-en-3-one dehydrogenase from Sterolibacterium denitrificans"  OPUS 2016/21/B/ST4/03798 - principal investigator: Maciej Szaleniec, investigators: Agnieszka Rugor, Maciej Guzik, Jakub Barbasz, Kamila Sofińska

2015-2018 „2-oxoglutarate dependent oxygenases catalyzing atypical oxidative transformations - structural and mechanistic studies. ” OPUS-8 UMO-2014/15/B/NZ1/03331 – principal investigator: Tomasz Borowski, investigators: Beata Mrugała (PhD student), Anna Miłaczewska, Przemysław Porębski, Ewa Niedziałkowska, Krzysztof Lewiński

2015 – 2020 „2-Oxoglutarate dependent oxygenases in the biosynthesis of pharmacologically active alkaloids - structure, catalytic mechanisms and rational redesign ” SONATA BIS 4 UMO-2014/14/E/NZ1/00053 – principal investigator: Tomasz Borowski, investigators: Ewa Kot (PhD student), Anna Kluza (PhD student), Zuzanna Wojdyła (PhD student), Przemysław Porębski, Ewa Niedziałkowska

2012 – 2016 „Structure and function of acireductone dioxygenases - experimental and computational studies” OPUS UMO-2011/03/B/NZ1/04999 - principal investigator: Tomasz Borowski, investigators: Anna Miłaczewska (PhD student), Ewa Kot (PhD student), Katarzyna Chruszcz-Lipska, Bartosz Trzewik, Joanna Opalińska-Piskorz

2017-2019 „Novel functionalised biopolymers for medical applications”,  LIDER/0090/L-7/2015 –   project leader: Maciej Guzik, team: Kamila Sofińska, Tomasz Witko, Martyna Podobińska, Karolina Stępień.

2016-2019 „Lipase-mediated biosynthesis of novel lactose esters. Physicochemical and anticancer studies.” SONATA 2015/17/D/ST4/00514 –  project leader: Maciej Guzik, team: Jakub Staroń, Ewelina Cichoń, Justyna Prajsnar 

2015-2016 „Biocatalytic synthesis of sugar esters” KNOW –  project leader: Maciej Guzik

2013-2017 „The mechanism of regioselective oxidation of cholesterol derivatives by a novel molybdenum enzyme, steroid 25-OH dehydrogenase from Stereolibacterium denitrificans” SONATA 2012/05/D/ST4/00277  –  project leader: Maciej Szaleniec, team: Ewa Niedziałkowska, Anna Wójcik, Agnieszka Rugor (PhD student),  Jakub Staroń (PhD student), Mateusz Hochołowski

2012-2016 „Regioselective oxidation of cholesterol derivatives with a novel molybdoenzyme – 25-OH cholesterol dehydrogenase”,  LIDER/33/147/11/NCBR/2012  –   project leader: Maciej Szaleniec, team: Agnieszka Rugor (PhD student), Mateusz Tataruch (PhD student), Agnieszka Dudzik (PhD student), Natalia Zawada (PhD student), Daniel Knack, Ewa Niedziałkowska

2011 – 2013 „Modeling of catalytic activity of biological nanostructures - nonheme iron dioxygenases ” PRELUDIUM UMO-2011/01/N/ST4/02330 principal investigator: Anna Wójcik (PhD student), investigators: Tomasz Borowski

2010-2015 „Biotransformation useful in pharmaceutical and cosmetics industry”, POIG.01.03.01-00-158/09-00  – task leader: Maciej Szaleniec,  team: Mateusz Tataruch (PhD student), Agnieszka Dudzik (PhD student), Agnieszka Rugor (PhD student) 

2011 – 2014 „Iron enzymes involved in biosynthesis of antibiotics - molecular activity mechanisms ” OPUS UMO-2011/01/B/ST4/02620 – principal investigator: Ewa Brocławik, investigators: Tomasz Borowski, Mariusz Radoń

2009-2013 „Biocatalytic synthesis of chiral alkylaromatic and alkylheterocyclic alcohols by ethylbenzene dehydrogenase – theory and experiment”, N N204 269038 –  task leader: Maciej Szaleniec, team: Mateusz Tataruch (PhD student),  Agnieszka Dudzik (PhD student)

2006 – 2008 „Reaction mechanisms on selected mononuclear non-heme enzymes ” Ministry of Science and Higher Education habilitation grant -  principal investigator: Tomasz Borowski 

2005-2007 WP6 Network of Excelance IDECAT  -  team: Maciej Szaleniec (PhD student)

2005-2006  „Enzymatic biocatalitic processes - theory and experiment” Scientific network EKO-KAT  -  task leader: Maciej Szaleniec (PhD student), team: Andrzej Skoczowski, Małgorzata Witko

2005-2006 „Biocatalytic oxidation of ethylbenzene and its derivatives”  3 T09A 062 28  project leader: Małgorzata Witko, team: Maciej Szaleniec (PhD student)