Profil pracownika

Dr Przemysław Porębski

Pracownik IKiFP PAN od: 2014

Pokój: 234

Telefon: +48 12 63 95 158

E-mail: ncpporeb(at)cyf-kr.edu.pl

Tematyka badawcza:

Badanie zależności między strukturą a funkcją białek.
Rozwój algorytmów do budowy modeli makrocząsteczek.

Metodyka:

Krystalografia rentgenowska
Modelowanie porównawcze
Analizy ewolucyjne
Nauczanie maszynowe

Dalsze informacje:

Lista publikacji:

Chruszcz M, Mikolajczak K, Mank N, Majorek KA, Porebski PJ, Minor W.
Serum albumins-Unusual allergens.
Biochim Biophys Acta. 2013 Dec;1830(12):5375-81

Majorek KA, Porebski PJ, Dayal A, Zimmerman MD, Jablonska K, Stewart AJ, Chruszcz M, Minor W.
Structural and immunologic characterization of bovine, horse, and rabbit serum albumins.
Mol Immunol. 2012 Oct;52(3-4):174-82

Shabalin IG, Porebski PJ, Cooper DR, Grabowski M, Onopriyenko O, Grimshaw S, Savchenko A, Chruszcz M, Minor W.
Structure of anabolic ornithine carbamoyltransferase from Campylobacter jejuni at 2.7 Å resolution.
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Sep;68(Pt 9):1018-24

Chruszcz M, Chapman MD, Osinski T, Solberg R, Demas M, Porebski PJ, Majorek KA, Pomés A, Minor W.
Alternaria alternata allergen Alt a 1: a unique β-barrel protein dimer found exclusively in fungi.
J Allergy Clin Immunol. 2012 Jul;130(1):241-7.e9.

Niedzialkowska E, Wang F, Porebski PJ, Minor W, Higgins JM, Stukenberg PT.
Molecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres.
Mol Biol Cell. 2012 Apr;23(8):1457-66

Chruszcz M, Pomés A, Glesner J, Vailes LD, Osinski T, Porebski PJ, Majorek KA, Heymann PW, Platts-
Mills TA, Minor W, Chapman MD.
Molecular determinants for antibody binding on group 1 house dust mite allergens.
J Biol Chem. 2012 Mar 2;287(10):7388-98

Zheng H, Filippova EV, Tkaczuk KL, Dworzynski P, Chruszcz M, Porebski PJ, Wawrzak Z, Onopriyenko O, Kudritska M, Grimshaw S, Savchenko A, Anderson WF, Minor W.
Crystal structures of putative phosphoglycerate kinases from B. anthracis and C. jejuni.
J Struct Funct Genomics. 2012 Mar;13(1):15-26

Porebski PJ, Klimecka M, Chruszcz M, Nicholls RA, Murzyn K, Cuff ME, Xu X, Cymborowski M, Murshudov GN, Savchenko A, Edwards A, Minor W.
Structural characterization of Helicobacter pylori dethiobiotin synthetase reveals differences between family members.
FEBS J. 2012 Mar;279(6):1093-105

Cooper DR, Porebski PJ, Chruszcz M, Minor W.
X-ray crystallography: Assessment and validation of protein-small molecule complexes for drug discovery.
Expert Opin Drug Discov. 2011 Aug 1;6(8):771-782

Klimecka MM, Chruszcz M, Font J, Skarina T, Shumilin I, Onopryienko O, Porebski PJ, Cymborowski M, Zimmerman MD, Hasseman J, Glomski IJ, Lebioda L, Savchenko A, Edwards A, Minor W.
Structural analysis of a putative aminoglycoside N-acetyltransferase from Bacillus anthracis.
J Mol Biol. 2011 Jul 15;410(3):411-23


Lista depozytów PDB
3HHL, 3KZL, 3MLE, 3N0M, 3N0S, 3OP4, 3OT1, 3QXC, 3QXH, 3QXJ, 3QXS, 3QXX, 3QY0, 3SKS, 3SLB, 3SLF, 3T32, 3T7B, 3TPF, 3UEC, 3UED, 3UEE, 3UEF, 3UEG, 3UEH, 3UEI, 3UWD, 3V03, 3V08, 3V09, 3V48, 3V4D, 4DGT, 4DQ6, 4GQA, 4IQG, 4IW7, 4JSB, 4JVT, 4JXR, 4JXU, 4JYJ, 4JYK, 4JYL, 4KLW, 4KOR, 4KOW, 4KOY, 4QGL, 4TNN

2018

  • A. Kluza, E. Niedzialkowska, K. Kurpiewska, Z. Wojdyla, M. Quesne, E. Kot, P.J. Porebski, T. Borowski, "Crystal structure of thebaine 6-O-demethylase from the morphine biosynthesis pathway", Journal of Structural Biology, (2018) 229-235